Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies.
نویسندگان
چکیده
منابع مشابه
Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies.
We have investigated the feasibility of using human autoimmune antibodies to isolate and characterize specific nuclear ribonucleoprotein (nRNP) complexes. High titers of anti-nRNP antibodies occur in a syndrome called mixed connective tissue disease. IgG antibodies from two mixed connective tissue disease patients were used to construct affinity columns to isolate the antigenic complexes from r...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)50805-x